Article

<i>CXCL12</i>drives natural variation in coronary artery anatomy across diverse populations

2023-10-27

Abstract excerpt

To efficiently distribute blood flow to cardiac muscle, the coronary artery tree must follow a specific branching pattern over the heart. How this pattern arises in humans is unknown due to the limitations of studying human heart development. Here, we leveraged a natural variation of coronary artery anatomy, known as coronary dominance, in genetic association studies to identify the first known driver of human cor...

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Literature Corpus work: 6210ab25-8be2-564c-b254-ba93c2cca424
DOI: 10.1101/2023.10.27.23297507

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