Article

Subtyping psychotic disorders using a data-driven approach reveals divergent cortical and cellular signatures

2025-08-27

Abstract excerpt

<h4>ABSTRACT</h4> Structural brain abnormalities in psychosis are well-replicated but heterogenous posing a barrier to uncovering the pathophysiology, etiology, and treatment of psychosis. To parse neurostructural heterogeneity and assess for the presence of anatomically-derived subtypes, we applied a data-driven method, similarity network fusion (SNF), to structural neuroimaging data in a broad cohort of individ...

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Literature Corpus work: 439fd94c-1e39-5582-a4fe-a2b978b0f937
DOI: 10.1101/2025.08.26.672411

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