Article

In vivo challenges of anti-diabetic peptide therapeutics: Gastrointestinal stability, toxicity and allergenicity

2020-11-01

Abstract excerpt

A plethora of research has explored the potential of bioactive peptide as a new class of drug therapeutics, yet only a minute amount has successfully translated into clinical trials. Possible reasons may include several in vivo challenges such as the poor peptide bioavailability upon oral ingestion, peptide toxicity and peptide allergenicity. Bioinformatics offers a preliminary in silico prediction, screening and...

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Literature Corpus work: 616f4778-ff33-5d52-abd0-10941413b0b5
DOI: 10.1016/j.tifs.2020.09.005

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