Article
Peptide toxicity prediction.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2015
Gupta Sudheer, Kapoor Pallavi, Chaudhary Kumardeep, Gautam Ankur, Kumar Rahul, Raghava Gajendra P S
Abstract excerpt
Last decade has witnessed the revival of interest in peptides as potential therapeutics candidates. However, one of the bottlenecks in the success of therapeutic peptides in clinics is their toxicity towards eukaryotic cells. Therefore, considerable efforts have been made over the years both in wet and dry lab to overcome this limitation. With the advances in peptide synthesis, now it is possible to fine-tune the...
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