Article
Diffuse large B cell lymphoma: molecular targeted therapy.
International journal of hematology - 1 Nov 2012
Roschewski Mark, Dunleavy Kieron, Wilson Wyndham H
Abstract excerpt
Diffuse large B cell lymphoma (DLBCL) is a biologically heterogeneous disease and the most common subtype of B cell non-Hodgkin's lymphoma in the USA. Even though it is a curable lymphoma in advanced stages, up to 40 % of patients eventually relapse or fail to achieve remission. Improved understanding of the biologic complexity of DLBCL reveals a diverse range of oncogenic driver mutations and signaling pathways...
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