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Article

Pancreatic Cancer Metastases Harbor Evidence of Polyclonality.

Cancer discovery - 1 Oct 2015

Maddipati Ravikanth, Stanger Ben Z

Abstract excerpt

UNLABELLED: Studies of the cancer genome have demonstrated that tumors are composed of multiple subclones with varied genetic and phenotypic properties. However, little is known about how metastases arise and evolve from these subclones. To understand the cellular dynamics that drive metastasis, we used multicolor lineage-tracing technology in an autochthonous mouse model of pancreatic cancer. Here, we report...

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Source

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Identifiers

PMID: 26209539
DOI: 10.1158/2159-8290.CD-15-0120
PMCID: PMC4657730

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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