Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of clonal communication and heterogeneity in breast cancer

5 Jul 2019

Abstract excerpt

BACKGROUND: Cancer is a rapidly evolving, multifactorial disease that accumulates numerous genetic and epigenetic alterations. This results in molecular and phenotypic heterogeneity within the tumor, the complexity of which is further amplified through specific interactions between cancer cells. We aimed to dissect the molecular mechanisms underlying the cooperation between different clones. METHODS: We produced...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer Genomics and Diagnostics
Share to Cancer Research and Treatments

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31277602
DOI: 10.1186/s12885-019-5883-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 22 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of clonal communication and heterogeneity in breast cancerPMID 31277602Read ↗

Advances for studying clonal evolution in cancer.Semantic proximity Read ↗

Intratumoral heterogeneity: Clonal cooperation in epithelial-to-mesenchymal transition and metastasisSemantic proximity Read ↗

Transient commensal clonal interactions can drive tumor metastasis.Semantic proximity Read ↗

Experimental and spontaneous metastasis assays can result in divergence in clonal architectureSemantic proximity Read ↗

Fitness and transcriptional plasticity of human breast cancer single-cell-derived clonesSemantic proximity Read ↗

Synergistic inter-clonal cooperation involving crosstalk, co-option and co-dependency can enhance the invasiveness of genetically distant cancer clonesSemantic proximity Read ↗

High-resolution clonal mapping of multi-organ metastasis in triple negative breast cancerSemantic proximity Read ↗

Clonal populations of a human TNBC model display significant functional heterogeneity and divergent growth dynamics in distinct contexts.Semantic proximity Read ↗

DNA barcoding reveals diverse growth kinetics of human breast tumour subclones in serially passaged xenograftsSemantic proximity Read ↗

Breast cancer as an example of tumour heterogeneity and tumour cell plasticity during malignant progressionSemantic proximity Read ↗

Transient Commensal Clonal Interactions Can Drive Tumor MetastasisSemantic proximity Read ↗

Evidence of lateral transmission of aggressive features between different types of breast cancer cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.