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Transcriptomic Features of Bovine Blastocysts Derived by Somatic Cell Nuclear Transfer

16 Sept 2015

Abstract excerpt

Reprogramming incompletely occurs in most somatic cell nuclear transfer (SCNT) embryos, which results in misregulation of developmentally important genes and subsequent embryonic malfunction and lethality. Here we examined transcriptome profiles in single bovine blastocysts derived by in vitro fertilization (IVF) and SCNT. Different types of donor cells, cumulus cell and ear-skin fibroblast, were used to derive...

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PMID: 26342001
DOI: 10.1534/g3.115.020016

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