Article

Design and characterization of HIV-1 vaccine candidates to elicit antibodies targeting multiple epitopes

2025-01-09

Abstract excerpt

A primary goal in the development of an AIDS vaccine is the elicitation of broadly neutralizing antibodies (bNAbs) that protect against diverse HIV-1 strains. To this aim, germline-targeting immunogens have been developed to activate bNAb precursors and initiate the induction of bNAbs. While most pre-clinical germline-targeting HIV-1 vaccine candidates only include a single bNAb precursor epitope, an effective HIV...

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Literature Corpus work: 610a8dd3-48a2-5c5b-95fc-733d437743ce
DOI: 10.1101/2025.01.08.632013

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