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Article

HIV-1 vaccine immunogen design strategies

23 Jan 2015

Abstract excerpt

An effective human immunodeficiency virus type 1 (HIV-1) vaccine is expected to have the greatest impact on HIV-1 spread and remains a global scientific priority. Only one candidate vaccine has significantly reduced HIV-1 acquisition, yet at a limited efficacy of 31%, and none have delayed disease progression in vaccinated individuals. Thus, the challenge remains to develop HIV-1 immunogens that will elicit...

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PMID: 25616599
DOI: 10.1186/s12985-014-0221-0

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