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Article

Nucleus raphe magnus serotonin neurons bidirectionally control spinal nociceptive transmission in mice

2025-04-15

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Noxious stimuli are conveyed to and integrated in the dorsal horn of the spinal cord (DHSC) before being transmitted to supraspinal centers, where pain perception is generated. Descending pathways from the brainstem dynamically modulate this integration, either facilitating or inhibiting nociceptive information based on physiological, emotional, genetic and environmental fac...

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Literature Corpus work
60d876d3-152b-5840-8591-f6f9c26703a0
DOI
10.1101/2025.04.09.647804
Open publication

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Nucleus raphe magnus serotonin neurons bidirectionally control spinal nociceptive transmission in miceDOI 10.1101/2025.04.09.647804
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