Article

Migration through a small pore disrupts inactive chromatin organization in neutrophil-like cells

2018-06-05

Abstract excerpt

<h4>Background</h4> Mammalian cells are flexible and can rapidly change shape when they contract, adhere, or migrate. Their nucleus must be stiff enough to withstand cytoskeletal forces, but flexible enough to remodel as the cell changes shape. This is particularly important for cells migrating through constricted space, where the nuclear shape must change in order to fit through the constriction. This occurs man...

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Literature Corpus work: 7b1c7476-fc58-5ff3-9dde-062d5474b13d
DOI: 10.1101/339085

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