Article

Murine Fetal Tracheal Occlusion Increases Lung Basal Cells via Increased Yap Signaling

2021-09-22

Abstract excerpt

<h4>ABSTRACT</h4> Fetal endoscopic tracheal occlusion (FETO) is an emerging surgical therapy for congenital diaphragmatic hernia (CDH). Ovine and rabbit data suggested altered lung epithelial cell populations after TO with transcriptomic signatures implicating basal cells. To test this hypothesis, we deconvolved mRNA-seq data and used quantitative image analysis in fetal rabbit lungs to showed increased basal cell...

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Literature Corpus work: 6079b655-d388-51d9-8b15-f75907f68a87
DOI: 10.1101/2021.09.17.21263741

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