Article

The Tricuspid Valve is Transcriptionally Active During Prolonged Pressure Overload, Right-Sided Heart Failure, and Valve Regurgitation

2025-07-25

Abstract excerpt

<h4>Background</h4> Right-sided heart failure (RHF), in the presence of tricuspid valve regurgitation (TR), can result from left-sided heart failure (LHF), pulmonary hypertension (PH), or heart malformations. The occurrence of RHF and TR represents a critical indicator of hospitalization rates and all-cause mortality. However, RHF has remained understudied, specifically with respect to the tricuspid valve, with f...

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Literature Corpus work: 60458e4a-912b-52bc-8067-e1a35d89bc0b
DOI: 10.1101/2025.07.21.666043

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