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Article

A common gene signature of the right ventricle in failing rat and human hearts

5 Jul 2024

Abstract excerpt

The molecular mechanisms of progressive right heart failure are incompletely understood. In this study, we systematically examined transcriptomic changes occurring over months in isolated cardiomyocytes or whole heart tissues from failing right and left ventricles in rat models of pulmonary artery banding (PAB) or aortic banding (AOB). Detailed bioinformatics analyses resulted in the identification of gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39196177
DOI: 10.1038/s44161-024-00485-1

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