Article

Astrocyte-Derived TNF-α Activated Platelets Promote Cerebral Ischemia/Reperfusion Injury by Regulating RIP1/RIP3/AKT Signaling Pathway

2021-09-02

Abstract excerpt

<title>Abstract</title> <p>Ischemic stroke is a type of clinical syndrome caused by disruption of blood flow into the cerebral tissues, and is associated with high disability and mortality rates. Studies have established a pathological role of platelets in cerebral ischemia/reperfusion (I/R) injury, although the underlying mechanisms remain largely unclear. In the present study, we induced I/R in a mouse model vi...

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Literature Corpus work: 602ae767-b817-5120-8561-3872315f511b
DOI: 10.21203/rs.3.rs-849954/v1

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