Article

Integrated transcriptomic and proteomic profiling reveals the key molecular signatures of brain endothelial reperfusion injury

2022-11-02

Abstract excerpt

<title>Abstract</title> <p>Reperfusion after ischemic stroke often causes brain microvascular injury and blood-brain barrier disruption; however, the underlying mechanisms are unclear. Here, we performed transcriptomic and proteomic analyses on human cerebral microvascular endothelial cells following oxygen-glucose deprivation (OGD) or OGD plus recovery (OGD/R), to identify molecules and signaling pathways dysreg...

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Literature Corpus work: 4854cc7f-8120-5de6-8217-8e0a0a0b76db
DOI: 10.21203/rs.3.rs-2216319/v1

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