Article

CircRNA_0000927 promotes inflammatory response to neuronal injury via miR-126a-5p/PGC-1α axis in acute ischemic stroke

2022-12-01

Abstract excerpt

<h4>Purpose: </h4> We investigated the role of CircRNA_0000927 on the occurrence and development of acute ischemic stroke (AIS) and neuronal injury by targeting the miR-126a-5p/PGC-1α axis to find a novel clinical drug target and prediction and treatment of AIS. Methods The mouse AIS animal model was used in vivo experiments and hypoxia/reoxygenation cell model in vitro was established. Firstly, infarction volume...

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Literature Corpus work: a5679e60-0d4a-55cc-bad2-c063ee0b03d3
DOI: 10.21203/rs.3.rs-2307258/v1

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