Article
Butyrate ameliorates inflammation in colon biopsy samples of IBD patients and experimental colitis in mice involving RNA binding protein, AUF1-IL-27 axis and accelerating B1a to B10 polarization
2024-05-28
Abstract excerpt
The pathophysiology of Inflammatory Bowel Disease (IBD) is significantly influenced by the decline in B regulatory (B10) cells, which produce IL-10. Therefore, it is important to identify the key genes and pathways that regulate the B10 cell generation in order to develop more effective therapies. Here, we have shown that one of the short chain fatty acid, butyrate regulates the expression of RNA binding protein,...
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Identifiers and source
- Literature Corpus work
- 60064704-1b9f-51ca-b952-2b421d7264ba
- DOI
- 10.1101/2024.05.24.595646
