Article

Glucose uptake in pigment glia suppresses tau-induced inflammation and photoreceptor degeneration in <i>Drosophila</i>

2024-08-19

Abstract excerpt

Brain inflammation contributes to the pathogenesis of neurodegenerative diseases such as Alzheimer’s disease (AD). Glucose hypometabolism and glial activation are pathological features seen in AD brains; however, the connection between the two is not fully understood. Using a Drosophila model of AD, we identified that glucose metabolism in glia plays a critical role in neuroinflammation under disease conditions....

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Literature Corpus work: 5f514ed2-bbdb-5c6c-92f6-dbae2445b0d6
DOI: 10.1101/2024.08.14.607919

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