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High ratio of resident to exhausted CD4+ T cells predicts favorable prognosis and potentially better immunotherapeutic efficacy in hepatocellular carcinoma

2023-11-02

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<title>Abstract</title> <p><bold>Background:</bold> Tumor-infiltrating lymphocytes (TILs) are significantly implicated in regulating the tumor immune microenvironment (TIME) and immunotherapeutic response. However, little is known about the impact of the resident and exhausted status of TILs in hepatocellular carcinoma (HCC). <bold>Methods:</bold> Single-cell RNA sequencing data was applied to discover resident a...

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Literature Corpus work
dcd955c2-d739-5f48-b81a-17721f1382d7
DOI
10.21203/rs.3.rs-3524256/v1
Open publication

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High ratio of resident to exhausted CD4+ T cells predicts favorable prognosis and potentially better immunotherapeutic efficacy in hepatocellular carcinomaDOI 10.21203/rs.3.rs-3524256/v1
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