Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fast, hungry and unstable: finding the Achilles' heel of small-cell lung cancer.

Trends in molecular medicine - 1 Apr 2007

Hann Christine L, Rudin Charles M

Abstract excerpt

Over 95% of patients with small-cell lung cancer (SCLC) die within five years of diagnosis. The standard of care and the dismal prognosis for this disease have not changed significantly over the past 25 years. Some of the characteristics of SCLC that have defined it as a particularly virulent form of cancer -- rapid proliferation, excessive metabolic and angiogenic dependence, apoptotic imbalance and genetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Small Cell
Share to Cell Proliferation
Share to Cell Survival

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomal Instability

Share to Growth Substances

Share to Lung Neoplasms

Share to Neovascularization, Pathologic

Share to Protein Folding

Source

Open in PubMed Open full text

Identifiers

PMID: 17324626
DOI: 10.1016/j.molmed.2007.02.003
PMCID: PMC4124625

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fast, hungry and unstable: finding the Achilles' heel of small-cell lung cancer.PMID 17324626Read ↗

The molecular pathogenesis of small cell lung cancerSemantic proximity Read ↗

Small Cell Lung Cancer: State of the Art of the Molecular and Genetic Landscape and Novel PerspectiveSemantic proximity Read ↗

Signal pathways and precision therapy of small-cell lung cancerSemantic proximity Read ↗

Origins, genetic landscape, and emerging therapies of small cell lung cancer.Semantic proximity Read ↗

Small cell lung cancer: Novel treatments beyond immunotherapySemantic proximity Read ↗

Cellular and molecular biology of small cell lung cancer: an overview.Semantic proximity Read ↗

Advances in Small-Cell Lung Cancer (SCLC) Translational Research.Semantic proximity Read ↗

Molecular profiles of small cell lung cancer subtypes: Therapeutic implicationsSemantic proximity Read ↗

Small-cell lung cancer.Semantic proximity Read ↗

The Therapeutic Potential of DNA Damage Repair Pathways and Genomic Stability in Lung CancerSemantic proximity Read ↗

Metastatic organotropism in small cell lung cancerSemantic proximity Read ↗

The Evolving Scenario of ES-SCLC Management: From Biology to New Cancer Therapeutics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.