Article

Functional Recovery of the Germ Line Following Splicing Collapse

2021-06-05

Abstract excerpt

<h4>ABSTRACT</h4> Splicing introns from precursor-messenger RNA (pre-mRNA) transcripts is essential for translating functional proteins. Here, we report that the previously uncharacterized Caenorhabditis elegans protein MOG-7, acts as a pre-mRNA splicing factor. Depleting MOG-7 from the C. elegans germ line causes intron retention in the majority of germline-expressed genes, impeding the germ cell cycle, and ca...

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Literature Corpus work: 31e9f515-7887-590a-80be-3a574e27f043
DOI: 10.1101/2021.06.04.447173

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