Redox metabolism as a key driver of metacyclic promastigote to amastigote transition in Leishmania infantum.

Abstract excerpt

<title>Abstract</title> <p>Leishmania is a protozoan parasite causing leishmaniasis, a disease affecting millions globally. It is transmitted through bites from infected sand-flies, primarily of the Phlebotomus spp. or Lutzomyia spp. The parasite has two main life stages: the promastigote, found in the insect vector, and the amastigote, residing in the macrophages of the host. The mechanisms behind stage differen...

Topics

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• Computational Drug Discovery Methods
• Fungal Infections and Studies
• Malaria Research and Control
• Mosquito-borne diseases and control
• Neutrophil, Myeloperoxidase and Oxidative Mechanisms
• Research on Leishmaniasis Studies
• Synthesis and Biological Evaluation
• Trypanosoma species research and implications

Identifiers and source

Literature Corpus work

5ee9ee76-0021-59e5-a1c5-8c0d678707f8

DOI

10.21203/rs.3.rs-6980941/v1