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Novel <i>Plasmodium falciparum</i> metabolic network reconstruction identifies shifts associated with clinical antimalarial resistance

2017-03-23

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> Malaria remains a major public health burden and resistance has emerged to every antimalarial on the market, including the frontline drug artemisinin. Our limited understanding of Plasmodium biology hinders the elucidation of resistance mechanisms. In this regard, systems biology approaches can facilitate the integration of existing experimental knowledge and further unders...

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Literature Corpus work
b3244df4-a0b6-5054-813b-a7d38c128971
DOI
10.1101/119941
Open publication

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Novel <i>Plasmodium falciparum</i> metabolic network reconstruction identifies shifts associated with clinical antimalarial resistanceDOI 10.1101/119941
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