Article

Blockade of IL-6 inhibits tumor immune evasion and improves anti–PD-1 immunotherapy

2022-03-09

Abstract excerpt

<h4>Background: </h4> Long-standing inflammatory bowel disease predisposes to the development of colorectal cancer (CRC). Interleukin (IL) -6, a pivotal link between chronic inflammation and tumor progression, has recently been recognized as a potential target. The effect of IL-6 on proliferation and metastasis of CRC by activating STAT3 pathway has been widely demonstrated in recent years, but few on mediating tu...

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Literature Corpus work: 5e88efb3-e16f-5c77-929f-bdb402d5f515
DOI: 10.21203/rs.3.rs-1420368/v1

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