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Article

A Potential Role of IL-6/IL-6R in the Development and Management of Colon Cancer

24 Apr 2021

Abstract excerpt

Colorectal cancer (CRC) is the third most frequent cancer worldwide and the second greatest cause of cancer deaths. About 75% of all CRCs are sporadic cancers and arise following somatic mutations, while about 10% are hereditary cancers caused by germline mutations in specific genes. Several factors, such as growth factors, cytokines, and genetic or epigenetic alterations in specific oncogenes or tumor-suppressor...

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PMID: 33923292
DOI: 10.3390/membranes11050312

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