Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lactobacillus intestinalis facilitates tumor-derived CCL5 to recruit dendritic cell and suppress colorectal tumorigenesis

8 Jan 2025

Abstract excerpt

Gut microbes play a crucial role in regulating the tumor microenvironment (TME) of colorectal cancer (CRC). Nevertheless, the deep mechanism between the microbiota-TME interaction has not been well explored. In this study, we for the first time discovered that Lactobacillus intestinalis (L. intestinalis) effectively suppressed tumor growth both in the AOM/DSS-induced CRC model and the ApcMin/+ spontaneous adenoma...

Topics

Join the communities discussing this publication.

Cancer Immunotherapy and Biomarkers
Gut microbiota and health
Immune cells in cancer

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 39773173
DOI: 10.1080/19490976.2024.2449111

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lactobacillus intestinalis facilitates tumor-derived CCL5 to recruit dendritic cell and suppress colorectal tumorigenesisPMID 39773173Read ↗

Interaction between microbiota and immunity and its implication in colorectal cancerSemantic proximity Read ↗

Identification of the Crucial Role of CCL22 in F. nucleatum-Related Colorectal Tumorigenesis that Correlates With Tumor Microenvironment and Immune Checkpoint TherapySemantic proximity Read ↗

Novel insights into microbiome in colitis and colorectal cancerSemantic proximity Read ↗

Immunologic Drivers and Restraints in Colitis-Associated Colorectal CancerSemantic proximity Read ↗

Suppressed oncogenic molecules involved in the treatment of colorectal cancer by fecal microbiota transplantationSemantic proximity Read ↗

Secretion Inhibition of CCL2 by Decorin in colorectal cancer tumor-associated macrophages and the synergistic therapeutic effect with PD-1inhibitorSemantic proximity Read ↗

Identify CCL20 as the key immune microenvironment regulator in APC-mutation colon cancer by sc-RNA data analysis.Semantic proximity Read ↗

The Association Between Gut Microbiota, Toll-Like Receptors, and Colorectal CancerSemantic proximity Read ↗

Contribution of TLR signaling to the pathogenesis of colitis-associated cancer in inflammatory bowel diseaseSemantic proximity Read ↗

Inflammation and Cancer: A Temporal Perspective on Emerging Cellular and Molecular Mechanisms, Focusing on Gastrointestinal CancersSemantic proximity Read ↗

The Association between Gut Microbiota and Intestinal Toll-like Receptors Genes Expression in Adenomatous and Colorectal Cancerous patientsSemantic proximity Read ↗

Biological Roles of Toll-Like Receptors and Gut Microbiota In Colorectal CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.