Article

Genome-scale metabolic model predicts mechanistic differences in metabolic gradient of spatially resolved small intestine villi

2023-06-26

Abstract excerpt

<h4>ABSTRACT</h4> Studying the spatial metabolic gradient provides significant opportunities for understanding the spatial division of labor within the tissue microenvironment. Enterocytes have the capacity to perform serial oxidation and conjugation reactions for detoxification, making the small intestine important as one of the first-pass metabolic organs. Recently, the enterocyte metabolic gradient was found t...

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Literature Corpus work: 5e6594d1-5ecb-54b0-ad79-d77fe85fa732
DOI: 10.1101/2023.06.22.546161

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