Article

Identification and characterization of the <i>de novo</i> methyltransferases for eukaryotic N <sup>6</sup> -methyladenine (6mA)

2024-03-25

Abstract excerpt

<h4>ABSTRACT</h4> DNA N 6 -adenine methylation (6mA) is rediscovered as an important epigenetic mark in eukaryotes. We previously identified the MT-A70 family member AMT1 as the maintenance methyltransferase (MTase), but the identity of the de novo MTase(s) for 6mA establishment remains unidentified. The unicellular model eukaryote Tetrahymena thermophila offers a unique opportunity for studying de novo methy...

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Literature Corpus work: 5e5a4a4a-cd90-5b24-bc7f-a403235b9ac5
DOI: 10.1101/2024.03.25.586193

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