Article

N6-methyldeoxyadenosine is a transgenerational epigenetic mark protecting DNA from deletion

2026-02-16

Abstract excerpt

<h4>SUMMARY</h4> DNA N6-adenine methylation (6mA) is emerging as an important DNA modification present in all eukaryotic kingdoms, where its roles mostly involve transcriptional regulation and chromatin modification. Here, we demonstrate a distinct role for 6mA in Paramecium tetraurelia . We find that it is a trans-generational epigenetic mark which distinguishes host DNA from invasive elements, protecting the f...

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Literature Corpus work: 7416505c-e3a5-58bd-a854-dafc647ecfe7
DOI: 10.64898/2026.02.13.705781

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