Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

USP9X controls translation efficiency via deubiquitination of eukaryotic translation initiation factor 4A1.

Nucleic acids research - 25 Jan 2018

Li Zengxia, Cheng Zhao, Raghothama Chaerkady, Cui Zhaomeng, Liu Kaiyu, Li Xiaojing, Jiang Chenxiao, Jiang Wei, Tan Minjia, Ni Xiaohua, Pandey Akhilesh, Liu Jun O, Dang Yongjun

Abstract excerpt

Controlling translation initiation is an efficient way to regulate gene expression at the post-transcriptional level. However, current knowledge regarding regulatory proteins and their modes of controlling translation initiation is still limited. In this study, we employed tandem affinity purification and mass spectrometry to screen for unknown proteins associated with the translation initiation machinery....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Eukaryotic Initiation Factors
Share to HeLa Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to MCF-7 Cells

Share to Protein Biosynthesis

Share to RNA Interference

Share to Substrate Specificity

Share to Ubiquitin Thiolesterase

Share to Ubiquitination

Source

Open in PubMed Open full text

Identifiers

PMID: 29228324
DOI: 10.1093/nar/gkx1226
PMCID: PMC5778534

Genes

XIAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

USP9X controls translation efficiency via deubiquitination of eukaryotic translation initiation factor 4A1.PMID 29228324Read ↗

Cellular functions, molecular signalings and therapeutic applications: Translational potential of deubiquitylating enzyme USP9X as a drug target in cancer treatmentSemantic proximity Read ↗

Roles of USP9X in cellular functions and tumorigenesis (Review)Semantic proximity Read ↗

The X-linked deubiquitinase USP9X is an integral component of centrosome.Semantic proximity Read ↗

Spotlights on ubiquitin-specific protease 12 (USP12) in diseases: from multifaceted roles to pathophysiological mechanismsSemantic proximity Read ↗

Ubiquitin-Specific Peptidase 7: A Novel Deubiquitinase That Regulates Protein Homeostasis and CancersSemantic proximity Read ↗

Upf proteins: highly conserved factors involved in nonsense mRNA mediated decay.Semantic proximity Read ↗

Emerging Role of Ubiquitin-Specific Protease 19 in Oncogenesis and Cancer DevelopmentSemantic proximity Read ↗

Ubiquitin specific peptidase 5 regulates colorectal cancer cell growth by stabilizing Tu translation elongation factorSemantic proximity Read ↗

USP5: Comprehensive insights into structure, function, biological and disease-related implications, and emerging therapeutic opportunitiesSemantic proximity Read ↗

USP13: Multiple Functions and Target InhibitionSemantic proximity Read ↗

USP39 promotes tumorigenesis by stabilizing and deubiquitinating SP1 protein in hepatocellular carcinomaSemantic proximity Read ↗

Two Independent Mechanisms Promote Expression of an N-terminal Truncated USP18 Isoform with Higher DeISGylation Activity in the NucleusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.