Article

Atypical B cells are a normal component of immune responses to vaccination and infection in humans

2020-05-28

Abstract excerpt

The full diversity of the circulating human B cell compartment is unknown. Flow cytometry analysis suggests that in addition to naïve and memory B cells, there exists a population of CD11c + , CD27 − CD21 − “atypical” B cells, that are associated with chronic or recurrent infection and autoimmunity. We used single cell RNA-seq approaches to examine the diversity of both antigen-specific B cells and total B cell...

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Literature Corpus work: 5e30e231-202a-53e3-ae4b-9a0e3a94c4b9
DOI: 10.1101/2020.05.28.120808

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