Article

Lymphoid origin of intrinsically activated plasmacytoid dendritic cells in mice

2018-04-28

Abstract excerpt

We identified a novel mouse plasmacytoid dendritic cell (pDC) lineage derived from the common lymphoid progenitors (CLPs) that is dependent on expression of Bcl11a . These CLP-derived pDCs, which we refer to as “B-pDCs”, have a unique gene expression profile that includes hallmark B cell genes, normally not expressed in conventional pDCs. Despite expressing most classical pDC markers such as SIGLEC-H and PDCA1, B...

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Literature Corpus work: 5e205a6c-dcd4-54d7-b9de-fb1b5a571ec1
DOI: 10.1101/310680

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