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ARL3 GTPases facilitate ODA16 unloading from IFT in motile cilia

4 Sept 2024

Abstract excerpt

Eukaryotic cilia and flagella are essential for cell motility and sensory functions. Their biogenesis and maintenance rely on the intraflagellar transport (IFT). Several cargo adapters have been identified to aid IFT cargo transport, but how ciliary cargos are discharged from the IFT remains largely unknown. During our explorations of small GTPases ARL13 and ARL3 in Trypanosoma brucei , we found that ODA16, a...

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PMID: 39231220
DOI: 10.1126/sciadv.adq2950

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ARL3 GTPases facilitate ODA16 unloading from IFT in motile ciliaPMID 39231220Read ↗

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