Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The small GTPases ARL-13 and ARL-3 coordinate intraflagellar transport and ciliogenesis.

The Journal of cell biology - 14 Jun 2010

Li Yujie, Wei Qing, Zhang Yuxia, Ling Kun, Hu Jinghua

Abstract excerpt

Intraflagellar transport (IFT) machinery mediates the bidirectional movement of cargos that are required for the assembly and maintenance of cilia. However, little is known about how IFT is regulated in vivo. In this study, we show that the small guanosine triphosphatase (GTPase) adenosine diphos...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Biological Transport
Share to Caenorhabditis elegans Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Flagella

Share to Histone Deacetylases

Share to Kinesins

Share to Monomeric GTP-Binding Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 20530210
DOI: 10.1083/jcb.200912001
PMCID: PMC2886347

Genes

HDAC6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20530210-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The small GTPases ARL-13 and ARL-3 coordinate intraflagellar transport and ciliogenesis.PMID 20530210Read ↗

Joubert syndrome Arl13b functions at ciliary membranes and stabilizes protein transport in <i>Caenorhabditis elegans</i>Semantic proximity Read ↗

The WD repeat-containing protein IFTA-1 is required for retrograde intraflagellar transport.Semantic proximity Read ↗

Regulation of ciliary retrograde protein trafficking by the Joubert syndrome proteins ARL13B and INPP5E.Semantic proximity Read ↗

GTP-binding of ARL-3 is activated by ARL-13 as a GEF and stabilized by UNC-119Semantic proximity Read ↗

Arl3 regulates ODA16-mediated intraflagellar transport in motile cilia biogenesisSemantic proximity Read ↗

Role for the IFT-A Complex in Selective Transport to the Primary Cilium.Semantic proximity Read ↗

Architecture of the IFT ciliary trafficking machinery and interplay between its componentsSemantic proximity Read ↗

The G protein alpha Chaperone and Guanine-Nucleotide Exchange Factor RIC-8 Regulates Cilia Morphogenesis in <i>Caenorhabditis elegans</i> Sensory NeuronsSemantic proximity Read ↗

ARL3 Mutations Cause Joubert Syndrome by Disrupting Ciliary Protein CompositionSemantic proximity Read ↗

Arl13b and the exocyst interact synergistically in ciliogenesis.Semantic proximity Read ↗

Ciliary ARL13B Is Essential for Vision and Morphogenesis of Cone Outer Segments.Semantic proximity Read ↗

Intraflagellar transport: from molecular characterisation to mechanismSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.