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<i>otpb</i> functions in a Lef1-dependent transcriptional network required for expression of the stress response inhibitor <i>crhbp</i> in the zebrafish hypothalamus

2023-06-09

Abstract excerpt

The vertebrate hypothalamus regulates physiological and behavioral responses to environmental stimuli through the function of evolutionarily-conserved neuronal subpopulations. Our previous work found that mutation of zebrafish lef1 , which encodes a transcriptional mediator of the Wnt signaling pathway, leads to the loss of hypothalamic neurons and behavioral phenotypes that are both associated with stress-relate...

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Literature Corpus work
5e1a804d-d84e-5b75-bbd4-48c3a41f8c07
DOI
10.1101/2023.06.07.544119
Open publication

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<i>otpb</i> functions in a Lef1-dependent transcriptional network required for expression of the stress response inhibitor <i>crhbp</i> in the zebrafish hypothalamusDOI 10.1101/2023.06.07.544119
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