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Article

Specification of hypothalamic neurons by dual regulation of the homeodomain protein Orthopedia.

Development (Cambridge, England) - 1 Dec 2007

Blechman Janna, Borodovsky Nataliya, Eisenberg Mark, Nabel-Rosen Helit, Grimm Jan, Levkowitz Gil

Abstract excerpt

In the developing hypothalamus, a variety of neurons are generated adjacent to each other in a highly coordinated, but poorly understood process. A critical question that remains unanswered is how coordinated development of multiple neuronal types is achieved in this relatively narrow anatomical region. We focus on dopaminergic (DA) and oxytocinergic (OT) neurons as a paradigm for development of two prominent...

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Identifiers

PMID: 18003738
DOI: 10.1242/dev.011262

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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