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Article

A peek inside the neurosecretory brain through <i>Orthopedia</i> lenses

26 Aug 2008

Abstract excerpt

The wealth of expression and functional data presented in this overview discloses the homeogene Orthopedia (Otp) as critical for the development of the hypothalamic neuroendocrine system of vertebrates. Specifically, the results depict the up-to-date portrait of the regulation and functions of Otp. The development of neuroendocrine nuclei relies on Otp from fish to mammals, as demonstrated for several peptide and...

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PMID: 18729222
DOI: 10.1002/dvdy.21668

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