Article

Disentangling the Amyloid Pathways: A Mechanistic Approach to Etiology

2019-11-19

Abstract excerpt

Amyloids are fibrillar protein aggregates that are associated with diseases such as Alzheimer’s disease, Parkinson’s disease, type II diabetes and Creutzfeldt–Jakob disease. The process of amyloid aggregation involves three pathological protein transformations; from natively-folded conformation to the cross-β conformation, from biophysically soluble to insoluble, and from biologically functi...

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Literature Corpus work: a2a68c84-ebc3-555b-a6f6-f378f5b9b7a5
DOI: 10.20944/preprints201909.0273.v2

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