Article

Structural Determinant of β-Amyloid Formation: From Transmembrane Protein Dimerization to β-Amyloid Aggregates

2022-10-06

Abstract excerpt

Most neurodegenerative diseases have the characteristics of proteinopathies, i.e. they cause lesions to appear in vulnerable regions of the nervous system, corresponding to protein aggregates that progressively spread through the neuronal network as the symptoms progress. Alzheimer's disease is one of these proteinopathies. It is characterized by two lesions, neurofibrillary tangles (NFTs) and senile plaques, form...

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Literature Corpus work: f34ee0b5-c830-5250-b67d-475bb5f9b8b3
DOI: 10.20944/preprints202210.0056.v1

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