Article

CNTNAP4 signaling regulates osteosarcoma disease progression

2022-08-27

Abstract excerpt

Improved treatment strategies for sarcoma rely on clarification of the molecular mediators of disease progression. Recently, we reported that the secreted glycoprotein NELL-1 modulates osteosarcoma (OS) disease progression in part via altering the sarcomatous extracellular matrix (ECM) and cell-ECM interactions. Of known NELL-1 interactor proteins, Contactin-associated protein-like 4 (Cntnap4) encodes a member of...

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Literature Corpus work: 5dbdf0d9-c990-5ce1-bee7-ab5bcb819fe6
DOI: 10.1101/2022.08.26.505419

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