Article

Upper and Lower Respiratory Tract Compartmentalization in Pediatric Stem Cell Transplantation

2025-10-17

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Rationale</h4> Lung injury after hematopoietic stem cell transplantation (HCT) occurs due to infection, chemotherapy toxicity, and alloreactive inflammation. Analyses of bronchoalveolar lavage (BAL) fluid have revealed dominant pathobiologic signatures, but minimally-invasive diagnostics are needed. <h4>Objectives</h4> To determine whether microbiome and gene expression perturbations are s...

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Literature Corpus work: 5db300c6-f012-5ce5-bd30-bc10994fb598
DOI: 10.1101/2025.10.15.25336763

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