Article

Pulmonary microbiome and transcriptome signatures reveal distinct pathobiologic states associated with mortality in two cohorts of pediatric stem cell transplant patients

2023-11-30

Abstract excerpt

<h4>ABSTRACT</h4> Lung injury is a major determinant of survival after pediatric hematopoietic cell transplantation (HCT). A deeper understanding of the relationship between pulmonary microbes, immunity, and the lung epithelium is needed to improve outcomes. In this multicenter study, we collected 278 bronchoalveolar lavage (BAL) samples from 229 patients treated at 32 children’s hospitals between 2014-2022. Using...

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Literature Corpus work: 806085a1-0ef9-513f-be11-cc0366915a1d
DOI: 10.1101/2023.11.29.23299130

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