Article
Single‐cell RNA sequencing of peripheral blood mononuclear cells from bronchopulmonary dysplasia
1 Mar 2025
Abstract excerpt
BACKGROUND: Bronchopulmonary dysplasia (BPD) is a severe respiratory disease that primarily affects premature infants, characterized by persistent inflammation and abnormal immune activation. This study aimed to elucidate the immunological mechanisms underlying BPD by integrating single-cell RNA sequencing with T/B cell receptor profiling of peripheral blood mononuclear cells (PBMCs) from preterm infants with...
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