Article

Distinct respiratory tract biological pathways characterizing ARDS molecular phenotypes

2022-04-05

Abstract excerpt

<h4>Background</h4> Two molecular phenotypes of the acute respiratory distress syndrome (ARDS) with divergent clinical trajectories and responses to therapy have been identified. Classification as “hyperinflammatory” or “hypoinflammatory” depends on plasma biomarker profiling. Differences in pulmonary biology underlying these phenotypes are unknown. <h4>Methods</h4> We analyzed tracheal aspirate (TA) RNA sequenc...

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Literature Corpus work: 028879b9-eb83-59ab-aacd-0aa29c71bb4e
DOI: 10.1101/2022.03.31.22272425

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