Article

Association Between Genetically Predicted Expression of TPMT and Azathioprine Adverse Events

2023-01-13

Abstract excerpt

Polymorphisms thiopurine-S-methyltransferase ( TPMT ) and nudix hydrolase 15 ( NUDT15 ) can increase the risk of azathioprine myelotoxicity, but little is known about other genetic factors that increase risk for azathioprine-associated side effects. PrediXcan is a gene-based association method that estimates the expression of individuals’ genes and examines their correlation to specified phenotypes. As proof of co...

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Literature Corpus work: 5d30d8ce-eb0f-5785-a5d1-cb16148293f7
DOI: 10.21203/rs.3.rs-2444787/v1

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