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Autoimmune-like CD8⁺ T Cell Responses Drive Atherosclerotic Plaque Instability and Predict Cardiovascular Events

2026-04-29

Abstract excerpt

<h4>Background and aims</h4> Atherosclerotic plaque rupture is a major cause of myocardial infarction and stroke. However, the precise drivers of plaque destabilisation remain elusive. We hypothesised that antigen-driven, autoimmune-like T cell responses are central to the destabilisation and rupture of atherosclerotic plaques. <h4>Methods</h4> To dissect T cell responses specifically in unstable compared to sta...

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Literature Corpus work
5d300705-f28c-5b73-a1de-9fb31a2ecf66
DOI
10.64898/2026.04.26.720043
Open publication

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Autoimmune-like CD8⁺ T Cell Responses Drive Atherosclerotic Plaque Instability and Predict Cardiovascular EventsDOI 10.64898/2026.04.26.720043
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