Article
Virus-Associated CD8+ T-Cells Are Not Activated Through Antigen-Mediated Interaction Inside Atherosclerotic Lesions.
Arteriosclerosis, thrombosis, and vascular biology - 1 Jun 2024
de Jong Maaike J M, Schaftenaar Frank H, Depuydt Marie A C, Lozano Vigario Fernando, Janssen George M C, Peeters Judith A H M, Goncalves Lauren, Wezel Anouk, Smeets Harm J, Kuiper Johan, Bot Ilze, van Veelen Peter, Slütter Bram
Abstract excerpt
INTRODUCTION: Viral infections have been associated with the progression of atherosclerosis and CD8+ T-cells directed against common viruses, such as influenza, Epstein-Barr virus, and cytomegalovirus, have been detected inside human atherosclerotic lesions. These virus-specific CD8+ T-cells have been hypothesized to contribute to the development of atherosclerosis; however, whether they affect disease...
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