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Article

Mechanisms of aging in senescence-accelerated mice.

Genome biology - 1 Jan 2005

Carter Todd A, Greenhall Jennifer A, Yoshida Shigeo, Fuchs Sebastian, Helton Robert, Swaroop Anand, Lockhart David J, Barlow Carrolee

Abstract excerpt

BACKGROUND: Progressive neurological dysfunction is a key aspect of human aging. Because of underlying differences in the aging of mice and humans, useful mouse models have been difficult to obtain and study. We have used gene-expression analysis and polymorphism screening to study molecular senescence of the retina and hippocampus in two rare inbred mouse models of accelerated neurological senescence (SAMP8 and...

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Identifiers

PMID: 15960800
DOI: 10.1186/gb-2005-6-6-r48
PMCID: PMC1175968

Genes

CCL19

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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